Pinnick Oxidation
The Pinnick oxidation also called Pinnick–Kraus oxidation is a reaction in which aldehydes (aliphatic, aromatic, saturated, or unsaturated) are oxidized into their corresponding carboxylic acids using sodium chlorite(NaClO2) under mild acidic conditions. The Jones oxidation, PDC, ruthenium tetroxide, etc. are all capable of the one-step oxidation of alcohols to carboxylic acids, but their reaction conditions tend to be too harsh to be used for polyfunctionalized compounds in the late stage of synthesis. So, milder and stepwise oxidation methods are often used instead.
Mechanism of Pinnick Oxidation
Examples of Pinnick Oxidation
