Piancatelli's Reaction, Mechanism and Examples

Piancatelli's Reaction, Mechanism and Examples

Piancatelli's Reaction

The Piancatelli rearrangement is a chemical reaction involving the transformation of 2-furylcarbinols into 4-hydroxycyclopentenones. This method was developed by Italian chemist Giovanni Piancatelli in 1976.
Piancatelli Reaction

Mechanism of Piancatelli's Reaction

The mechanism of this reaction is proposed to be a 4-π electrocyclization very much like the Nazarov cyclization reaction.
Piancatelli Rearrangement Mechanism


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